Dunad’s unique small molecule platform induces targeted degradation of disease-causing proteins via direct modulation of the target protein’s surface topology. The Company’s novel molecular approach, based on mono-valent small molecules, is fully tunable to be exquisitely selective for the target, and is underpinned by a target-class agnostic mechanism of action that is distinct from traditional mechanisms of targeted protein degradation.
The Company’s drug pipeline is powered by its expanding 4-pillar proprietary platform:
Proprietary Degradation Technology
Expanding the frontiers of our plug-and-play mono-valent degrader platform
Proprietary Screening Library
Accelerating Hit ID against novel targets
Unlocking previously inaccessible degradation targets via global and multi-dimensional profiling of the proteome
Driving the best drug candidates through the development
Dunad is focusing on targets for which degradation is the optimal mechanism of action, and inhibition of the target’s activity alone is insufficient to elicit the maximum therapeutic effect.
While the unique MOA and compositions of our platform are expected to unlock access to the previously undruggable targets, our platform also enables development of orally bioavailable and CNS-accessible degrader therapeutics, together expanding the frontiers of protein degradation space.
Dunad is continuing to expand its world-class scientific team with expertise across protein degradation, covalent therapeutics and proteomics, as well as it’s business leadership team.
Explore a career at Dunad
We’re hiring! Come work with our passionate team, pushing the boundaries of what small molecules are capable of.